That is an important consideration with metformin use in patients with liver disease?
A. There is a risk of lactic acidosis.
B. It may increase hepatic steatosis.
C. It has hepatoprotective effects.
D. It can lead to weight gain.
E. It requires an increased dose to maintain effectiveness.
Answer (1)
The most significant consideration with metformin use in patients with liver disease is the risk of lactic acidosis due to impaired liver function. While metformin may have some hepatoprotective effects and generally does not cause weight gain, it should be used cautiously in these patients. Monitoring and dose adjustment based on liver function are crucial. ;
